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NAD⁺ 1000 mg
$200.00
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Frequently Asked Questions
What is NAD⁺?
A coenzyme essential for energy metabolism and cellular repair.
Is NAD⁺ naturally occurring?
Yes, it is synthesized endogenously in all living cells.
What are its main research uses?
Studies on mitochondrial function, aging, and metabolic regulation.
How should NAD⁺ be stored?
Keep refrigerated at 2–8 °C for short‑term storage; −20 °C for long‑term. Avoid repeated freeze‑thaw cycles.
What is the shelf life of NAD⁺?
24 months in lyophilized form; 2–4 weeks after reconstitution if refrigerated.
Is NAD⁺ approved for human use?
No, it is strictly for research purposes.
Overview
Nicotinamide Adenine Dinucleotide (NAD⁺) is a vital coenzyme found in all living cells, central to redox reactions and energy metabolism. It functions as an electron carrier in oxidative phosphorylation and glycolysis, supporting mitochondrial ATP production and cellular repair. NAD⁺ also serves as a substrate for sirtuins and PARPs, linking metabolic state to genomic stability and longevity pathways.
History
Discovery: Identified in 1906 by Harden and Young during fermentation studies.
Biochemical Role: Established as a key coenzyme in oxidation–reduction reactions by the mid‑20th century.
Modern Research: Renewed interest in NAD⁺ restoration emerged with studies on aging, mitochondrial decline, and sirtuin activation.
Research Findings
Cellular Energy: Essential for ATP synthesis through electron transport.
DNA Repair: Acts as a substrate for PARP enzymes during genomic maintenance.
Sirtuin Activation: Regulates longevity‑associated proteins (SIRT1–SIRT7).
Metabolic Health: Supports glucose and lipid metabolism.
Neuroprotection: Demonstrated benefits in neuronal survival under oxidative stress.
Molecular Structure
References
Bogan KL, Brenner C. NAD⁺ Metabolism in Health and Disease. Trends Biochem Sci. 2008.
Verdin E. NAD⁺ in Aging, Metabolism, and Neurodegeneration. Science. 2015.
PubChem CID 5893 — Nicotinamide Adenine Dinucleotide.
ChemicalBook NAD⁺ Profile, 2026.
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